Non-indigenous and Invasive Species (NIS) are considered one of the major threats to the ecosystem functioning and one of the main drivers of biodiversity loss. Despite the advances in the understanding of introduction pathways, mechanisms of bio-invasions, and impacts of invasive species, the effective management and control of NIS still lag behind their spread. For such reason, LifeWatch ERIC has developed e-science tools to assist researchers, stakeholders, and citizens in deepening knowledge and obtaining rapid responses to mitigate the risks and impacts of NIS in the terrestrial and aquatic domains. On November 21, 2022, LifeWatch ERIC ICT staff, in collaboration with scientists already engaged in developing research activities on non-indigenous and invasive species using LifeWatch ERIC’s Virtual Research Environment facilities, organised the 4-hour computer-based Workshop: “e-Tools and resources to address key ecological questions on Non-indigenous and Invasive Species” during the SFE2 GFÖ EEF Joint Meeting, International Conference on Ecological Sciences. For more details, visit the event webpage.